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Faculty Profile Last Modified Time: 08:30:20 AM Mon, 23 Jul 2018   Contact Information Ken Chen Associated Profiles  Professor, Bioinformatics and Computational Biology, UT MD Anderson Cancer Center, Director of Bioinformatics - Khalifa Institute For Personalized Cancer Therapy (IPCT)   Feigin Center Tower, Room No.: 4.6094    kchen3@mdanderson.org     713-794-1348    Web Link    Neoplasms, Genome, Mutation, Genes, Tumors, High-Throughput Nucleotide Sequencing, Human Genome, Genomic Structural Variation    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Electrical and Computer Engineering University of Illinois, Urbana-Champaign 2004  ME Precision Instrument and Mechanics Tsinghua University 1999  BE Precision Instruments and Mechanics Tsinghua University 1996  Research and Expertise Research Interests   Having a background in machine learning, statistical signal processing, and cancer genomics, Dr. Chen's primary goal is to develop computational tools to analyze and interpret human genomics and clinical data towards the realization of genomic medicine. He has designed, developed, and co-developed a set of computational tools such as BreakDancer, TIGRA, CREST, BreakTrans, BreakFusion, PolyScan, SomaticSniper, and VarScan that have been widely applied to characterize individual and population genomics in various large-scale next-generation sequencing projects such as those in the Cancer Genome Atlas (TCGA) and the 1000 Genomes Project. He is particularly interested in comprehensively and accurately constructing the genomes and the transcriptomes of various cancer cell populations towards understanding the heterogeneity and the evolution of cancer as a consequence of genetics and environment. He is also interested in developing integrative approaches to identify biomarkers that are useful for diagnosis and prognosis.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Training Grants Training in Precision Environmental Health Sciences (TPEHS) NLM Training Program in Biomedical Informatics & Data Science for Predoctoral and Postdoctoral Fellows  Research Consortia Gulf Coast Cluster for Single Cell Omics  Appointments Title Department / School Institution Professor Bioinformatics and Computational Biology MD Anderson Cancer Center

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