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Faculty Profile Last Modified Time: 09:54:43 AM Wed, 22 Apr 2020   Contact Information Sam Hanash Associated Profiles  Professor, Director and Distinguished Chair, Clinical Cancer Prevention, UT MD Anderson Cancer Center     shanash@mdanderson.org     713-745-5242    Web Link    Proteomics, Proteins, Neoplasms, Proteome, Genes, Biomarkers, Cells, Peptides    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Human Genetics University of Michigan 1976  MD Human Genetics American University of Beirut 1972  BS Human Genetics American University of Beirut 1972  Research and Expertise Research Interests   What is cancer proteomics? Cells in your body rely on molecules called proteins to carry out bodily tasks. Cancer cells also rely on proteins to do things such as grow and spread. Cancer proteomics analyzes blood, tumor and tissue samples to identify the proteins in cancer cells that differ from those in normal cells. If a protein is made in larger amounts in cancer cells than in normal cells, it suggests that the protein may play a role in causing cancer to develop or spread. How does the Proteomics platform contribute to our mission of ending cancer? When we find proteins that indicate there's cancer or that play an important role in cancer's progression, we want to further study the protein to see if it's a good target for diagnostic tests or treatment options like targeted therapies or immunotherapies, which can help shrink the cancer. What do you and the rest of your team leading the Proteomics platform do? There are millions of proteins made throughout your body, so finding unique cancer-related proteins means sorting through massive amounts of data. In fact, one drop of blood can provide us with enough data to fill a laptop computer. Our job is to identify cancer-related proteins and help investigators narrow down the massive list of potential targets into those that are most likely to be developed into effective diagnostic tests or cancer drugs. We have a dozen experts that run the proteomics equipment and process, store and analyze the data that comes out it.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Training Grants Computational Cancer Biology Training Program  Appointments Title Department / School Institution Professor, Director and Distinguished Chair Clinical Cancer Prevention UT MD Anderson Cancer Center

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