Some important problems currently being addressed in our lab are summarized here : Measuring phase changes in x-rays and their applications in quantitative imaging. With smaller wavelength in comparison to visible or IR regime, instrumentation and quantitative measurements become challenging for x-ray phase measurements. Theoretical, analytical and computational methods go hand-in-hand with instrumentations to address these problems. Optical phase retrieval - light transport models, instrumentation and algorithms Single photon detection- Significantly higher information can be achieved from each detected photon with smart photon counting detectors. How can this be effectively used in various areas of fundamental, applied physics, imaging and investigations in biology and medicine? Science and mathematical models behind human perception of scenes, images and how we make signal detection in a complex background. Psychophysics and human perception is a complex process with significant applications in a wide range of areas such as machine learning, artificial intelligence, defense and security medical imaging device and algorithm optimization, microscopy and general image analysis. Energy resolved x-ray detection and color x-ray imaging. Monte Carlo simulations and experimental feedback from current prototypes will advance the design for these next generation direct detection semiconducting detectors. Among applications, we are working towards methods for early cancer detection, fast x-ray microscopes, fast and low dose x-ray micro computed tomography, lens free wide-area microscopes, building blocks for machine learning in imaging, mathematical models for human observers. Extensive computational imaging platforms for virtual clinical trials. Inverse problems and advanced tomographic image reconstruction.
Publications/Creative Works
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