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Faculty Profile Last Modified Time: 02:22:28 PM Fri, 27 Mar 2020   Contact Information Christine Beeton Associated Profiles  Professor, Integrative Physiology, Director, Graduate Program, Immunology & Microbiology, Baylor College of Medicine   Mail Box: BCM335, Smith Medical Research Bldg., Room No.: S409    beeton@bcm.edu     (713) 798-5030    Web Link    Lab Webpage    Autoimmune Diseases, Therapeutic Targets and Drug Development, Ions and Ion Channels in Disease, Venom Peptides/Antioxidants Nanomaterials as Potential Therapeutics, T-Lymphocyte Targeted Immunotherapy, Fibroblast-Like Synoviocytes    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Immunology Aix-Marseille University 2001  BS, MS Biochemistry/Immunology Aix-Marseille University 1996  Research and Expertise Research Interests   Christine Beeton's lab is interested in all aspects of translational research surrounding autoimmune and other chronic inflammatory diseases. Our expertise includes the isolation and culture of primary human and rodent cells (lymphocytes, monocyte/macrophages, and other immune cells; fibroblast-like synoviocytes; myoblasts), functional assays ex vivo (proliferation, production and secretion of cytokines, chemokines, proteases, migration, invasion, cytotoxicity, and more) and in vivo (trafficking, production and secretion of cytokines, chemokines, proteases, and more), patch-clamp electrophysiology on excitable and non-excitable cells for identification of ion channels and pharmacology of novel ion channel modulators, and animal models of inflammatory diseases in rats and mice (active and adoptive delayed type hypersensitivity, active and adoptive acute experimental autoimmune encephalomyelitis, chronic-relapsing experimental autoimmune encephalomyelitis, collagen-induced arthritis, pristane-induced arthritis, and adjuvant-induced arthritis). Our current work revolves around two main topics: targeting potassium channels for the treatment of chronic diseases (multiple sclerosis, rheumatoid arthritis, and type 1 myotonic dystrophy) and using antioxidant nanomaterials for the treatment of T lymphocyte-mediated autoimmune diseases (multiple sclerosis and rheumatoid arthritis).  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Consortia Immunology Cluster  Appointments Title Department / School Institution Associate Professor Molecular Physiology & Biophysics Baylor College of Medicine

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