My research at UT has culminated in the establishment of the Diffusion Tensor Imaging Lab (MSB 6.532, (713-500-7683) which currently provides help to more than 10 different research active groups. The DTI lab is part of the MRI research wing of the department and its major role is promote and support the department MRI main research. The DTI lab provides computational support, training, processing and consultation on data acquisition, management, detailed and professional quality control measures for researchers, clinical center trials and complete processing of data acquired from many scanners, at different scales that span the mouse, rat and the human CNS. My main research focuses on developing specialized acquisition and computational techniques to enhance contrast and increase specificity of DTI. The fusion of DTI and MEG, fMRI, perfusion, conventional MRI and MRSI will be important to identify noninvasive markers for quantifying and localizing human neurodegenerative diseases such as multiple sclerosis (collaborative work with Drs Jerry Wolinsky, Ponnada A. Narayana and Flavia Nelson), neurodevelopmental disorders such as Spina Bifida and Dyslexia (collaborative work with Drs Jack Fletcher, Maureen Dennis, Andrew Papanicolaou, Larry Kramer, Susan Blaser), pediatric traumatic brain injury (collaborative work with Dr Linda Ewing-Cobbs), neurotoxins such as cocaine and MDM (collaborative work with Drs Gerry Moeller and Joel L Steinberg). Many other applications of DTI such as fetal brain maturation and development and clinical applications (stroke, tumors, epilepsy, Hypoxic injury) are also ongoing (collaborative work with Dr Rakesh K Gupta, Andrew Papanicolaou, Corwin Boake), modeling of spinal cord injury recovery and therapy (collaborative work with Dr Ponnada A. Narayana) and modeling of animal disease such as Parkinson's, ALS, HIV (collaborative work with Drs Michael Boska and Howard Gillerman). Other collaborative DTI and quantitative MRI applications to human CNS conditions such as Stroke (Sean Savitz), Stem Cell Therapy post Trauma (Charles Cox), Schizophrenia (Joel Steinberg), ADHD (Manzar Ashtari), Epilepsy (Eduardo Castillo) and Autism (Richard E. Frye).
Publications/Creative Works
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Affiliations
Research Consortia
John S. Dunn, Sr. Gulf Coast Consortium for Magnetic Resonance
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