Dr. Dineley studies: Alzheimer's disease, Parkinson's disease, and related amyloidopathies, tauopathies, synucleinopathies. Animal models for cognitive decline in neurodegenerative disease utilizing genetic and pharmacological manipulations. Cocaine abuse and cue-induced relapse following abstinence; protection with PPAR³ nuclear receptor agonism. Nuclear receptor (PPAR³), ERK MAPK, CREB, CBP, nicotinic acetylcholine receptors, protein-protein interactions. Omics approaches to generate hypotheses that test key players and mechanisms for cognitive and operant disorders resulting from aging, neurodegenerative disease, and drug abuse.
Publications/Creative Works
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Affiliations
Research Consortia
Gulf Coast Consortium for Theoretical and Computational Neuroscience
Gulf Coast Cluster for Translational Addiction Science
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