Paul M. Cinciripini, Ph.D. is Professor and Chair of the Department of Behavioral Science and Director of the Tobacco Treatment Program at the University of Texas MD Anderson Cancer Center. He has over 30 years of experience conducting basic and clinical research in the area of smoking cessation and nicotine psychopharmacology. Dr. Cinciripini has been the recipient of several NIH-, extramural- and industry-sponsored research grants and is the author of over 190 articles and book chapters. Dr. Cinciripini's major research includes studies of nicotine titration and compensation, psychophysiological effects of nicotine during stress, individual differences in the effects of nicotine on EEG and cardiovascular activity, genetic factors treatment outcome, pharmacogenetic effects of antidepressants during smoking cessation, and recent studies using startle probe and EEG/ERP methodology to examine the relations between genetics, emotional reactivity, nicotine exposure and nicotine withdrawal. He has also studied the effects of depression, coping behavior, and self-efficacy as well as genetic factors related to nicotine dependence and tested novel behavioral and pharmacological approaches for treatment. Examples of his work in this latter area include: the development of a "scheduled smoking" procedure and a recent application of this technology for delivery on a handheld computer; development of a smoking cessation video series for pregnant smokers; evaluating combination therapies using nicotine replacement, behavioral counseling, and other approaches; and testing novel pharmacological compounds, including anxiolytics, antidepressants, nicotine partial agonists, and cannabinoid antagonists. He is presently the PI on several NIH-funded clinical trials, including, "Evaluating New Nicotine Standards for Cigarettes (CENIC)," which addresses the best approach to reducing nicotine in cigarettes by comparing a gradual vs. immediate reduction to low levels of nicotine; and "Pharmacogenetics of Nicotine Addiction Treatment (PNAT)," which optimizes pharmacotherapeutic choices for individuals who wish to quit smoking.
Publications/Creative Works
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