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Faculty Profile Last Modified Time: 10:28:02 AM Thu, 14 Mar 2024   Contact Information Rolando E. Rumbaut Associated Profiles  Professor & Vice Chair for Research, Medicine, Director, Center for Translational Research on Inflammatory Diseases, Baylor College of Medicine   Michael E. DeBakey VA Medical Center, Building 109, Room No.: 226    rrumbaut@bcm.edu     713-798-0316    Web Link    Microvascular Inflammation, Platelets, Microvascular Thrombosis    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   Research in my laboratory aims to understand the mechanisms responsible for microvascular dysfunction in inflammation. Microvascular dysfunction contributes to disease severity in critically ill patients (i.e., sepsis, acute respiratory distress syndrome, reperfusion injury, etc), and there is a lack of specific treatment for these abnormalities. Over the past decade, my research has focused on the role of platelets in the microcirculation in inflammation, based on increasing evidence that platelets are key mediators of inflammation. We are studying the mechanisms linking inflammation and microvascular thrombosis in experimental sepsis and the role of platelets in the response to epithelial injury. I am also committed to promoting collaborative research and mentoring of early career investigators in the Center for Translational Research on Inflammatory Diseases (CTRID).  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Consortia Immunology Cluster  Appointments Title Department / School Institution Professor & Interim Section Chief Medicine Baylor College of Medicine

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