Hartley, Craig J. (Faculty Profile)

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Faculty Profile

Last Modified Time: 09:53:00 AM Tue, 7 Apr 2020

Contact Information
Craig J. Hartley	Associated Profiles
Professor Emeritus, Medicine and Cardiovascular Sciences, Baylor College of Medicine, Adjunct Professor, Bioengineering, Rice Univ.; Adjunct Assoc. Prof., Elecrtical & Mechanical Engineering, Univ. of Houston


chartley@bcm.edu (713) 798-4188 Web Link
Arterial Stiffness, Circuit Design, Doppler Ultrasound, Doppler, Cardiovascular Mechanics, Vascular Physiology in Mice, Physiologic Measurements in Mice, Coronary Vascular Reserve

Research and Expertise
Appointments

Research and Expertise

Research Interests

Since 1970 Dr. Hartley has been involved in the design, development, and application of ultrasonic instrumentation for cardiovascular measurements in man and in animal models of human diseases. His group designed the first high frequency (20 MHz) pulsed Doppler velocimeter and catheters to measure coronary blood flow velocity and reserve in man (1973), the first multichannel pulsed Doppler system and implantable probes to measure regional blood flow in chronically instrumented animals (1976), and the first tissue Doppler to measure ventricular wall thickening (myocardial strain) in animals (1981) and in man (1987). Since 1992, he has been developing and using similar methods noninvasively to measure blood flow velocity and arterial wall motion in mice with unprecedented precision (100 nm) and temporal resolution (100 us). His group recently showed that left main coronary flow reserve, measured noninvasively in mice, is reduced by many types of heart disease and loading and is a sensitive index of global cardiac function. The ultrasonic technology developed by Dr. Hartley's laboratory has been incorporated into many clinical and research systems.

Publications/Creative Works

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Appointments

Title	Department / School	Institution
Professor Emeritus	Medicine and Cardiovascular Sciences	Baylor College of Medicine

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