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Faculty Profile Last Modified Time: 09:32:16 AM Mon, 20 Apr 2020   Contact Information Lei Zheng Associated Profiles  Associate Professor, Center for Membrane Biology, Dept of Biochemistry & Molecular Biology, UT Health Science Center at Houston   6431 Fannin, Room No.: MSB 6.218    Lei.Zheng@uth.tmc.edu     713-500-6083    Web Link    Structural Biology of Membrane Transporters, Phospholipid Metabolism, Calcium Cation Antiporter Proteins (CaCAs)    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   The research of my laboratory focuses on structural characterization of integral membrane proteins. Membrane proteins are fundamentally important in for nearly all aspects of biological activity. These molecules control material and information communications across the cell membranes. However, their working mechanisms are less understood largely due to the notorious difficulties to study them structurally. We are currently focusing on two important membrane protein systems involved in Ca2+ homeostasis and phospholipid metabolism. We aim to understand structure, function and regulation of these membrane proteins by using a combination of biochemical and biophysical approaches, primarily X-ray crystallography.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia John S. Dunn, Sr. GCC for Magnetic Resonance GCC Cluster for Cellular and Molecular Biophysics  Appointments Title Department / School Institution Associate Professor Biochemistry & Molecular Biology UT Health Science Center at Houston

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