Rochelle and Max Levit Chair in Neurosciences, Professsor and Director, Center for Precision Biomedicine, UT Health Science Center at Houston, Director, Mathematics in Medicine Program, The Methodist Hospital Research Institute
Dr. Cristini has over 15 years of experience in working with biologists, pathologists, physicians, and imaging scientists to study tumor growth and invasion and chemotherapy drug transport by using a combined mathematical modeling and experimental/clinical approach, aimed at helping develop individualized modeling-aided treatment strategies. Notably, he is leading a multi-institutional research effort on developing tissue-scale mechanistic biophysical models for predicting tumor response to treatment in individual patients using standard clinical diagnostic measurements, such as histopathology, CT, and MRI. His current research projects include: Biophysical theories to predict the growth and invasion and drug response in local and metastatic cancers; Predictive tumor models using continuum, discrete, hybrid, and statistical approaches; Upscaling and downscaling framework (i.e., functionally linking biological behaviors at different scales); Drug pharmacokinetics and pharmacodynamics (PKPD) models.
Publications/Creative Works
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