Diehl's Macromolecular Systems Bioengineering Group studies the cooperative dynamics of proteins and their operation as highly organized and integrated assemblies; develops engineering approaches that enable model systems of natural multiprotein assemblies to be reconstructed in vitro while preserving the intricate molecular features of these assemblies; and uses instrumentation to investigate the collective protein dynamics of these systems with single-molecule precision. This research concentrates on in vitro modeling of intracellular trafficking and transport, and encoding the self-organized mechanics of internally driven filaments.
Publications/Creative Works
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