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Faculty Profile Last Modified Time: 02:09:12 PM Fri, 17 Apr 2020   Contact Information James T. Willerson Associated Profiles  President Emeritus and Teaching Staff, Texas Heart Institute     jwillerson@texasheart.org     (832) 355-4925    Web Link    Coronary Heart Disease, Angina, Myocardial Infarction, Genes, Cardiovascular Disease    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   Dr. Willerson's research work has concentrated on elucidating mechanisms responsible for the conversion from stable to unstable coronary heart disease syndromes, the prevention of unstable angina and acute myocardial infarction, the detection and treatment of unstable atherosclerotic plaques, and the discovery of the genes and abnormal proteins responsible for cardiovascular disease. In 2001, he and his colleagues at the Texas Heart Institute in Houston and at the Hospital Procardico in Rio de Janeiro, Brazil, began bone marrow-derived stem cell transplantation directly into the hearts of patients with severe heart failure. He and his colleagues have demonstrated objective and subjective evidence of clinical improvement, enhanced blood flow, and improved contractile function in the hearts of these patients. In May 2004, the work was expanded to the Stem Cell Center, Texas Heart Institute at St. Luke's Episcopal Hospital in Houston where clinical trials are being conducted for patients with severe heart injury and heart failure, peripheral vascular disease, as well as patients having suffered heart attacks.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia John S. Dunn GCC for Chemical Genomics Gulf Coast Cluster for Regenerative Medicine  Appointments Title Department / School Institution President Emeritus and Teaching Staff THI Leadership Texas Heart Institute

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